Registration for May 19 Public Comment

Public comment periods will be hosted by the IOM Committee on Ethical and Social Policy Considerations of Novel Techniques for Prevention of Maternal Transmission on Mitochondrial DNA Diseases on May 19, 2015 between 10:00am – 12:00pm ET. Please note that public comments will be limited to 3 minutes per speaker. Upon completing this registration, IOM staff will contact you with additional information. Should you be unable to participate in the public comment session, you can always submit feedback to the committee here by clicking on “Provide FEEDBACK on this project.” A second option for providing written comments, which allows commenters to include attachments, is to email MitoEthics@nas.edu.

The committee in particular requests that you address one or more of the following questions during your public comments:

What ethical and social issues are raised by proposed mitochondrial replacement therapy (MRT) techniques?
- Should MRT be considered germline modification?
- Is MRT different, from an ethical or social perspective, from modification of nuclear DNA?
Should there be a distinction between genetic modification for therapeutic/prevention purposes and genetic modification for enhancement purposes? If so, how should this distinction be defined and implemented?
What are the ethical and social issues that arise if a child is born with genetic material from three individuals?
How should current availability of alternative approaches – adoption and egg donation – factor into the assessment of allowing MRT trials to proceed?
What are the ethical and social issues if MRT clinical trials were to proceed?
- Ethical and social issues in providing “consent”
- Ethical and social issues of first-in-human investigation in women and for the creation of children.
- Other aspects of enrollment and tracking during a clinical trial

Following registration, study staff will be in contact with additional information about the public comment period and your scheduled time.

1. I would like to register to provide in-person comments to the committee on: *This question is required.

2. Please enter your contact information in the space provided. *This question is required.

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3. As part of a survey to help the committee consider mechanisms for receiving public comments, please indicate your preferences below: *This question is required.